產品詳情

  • 產品名稱：PurinergicReceptorP2X,Ligand-GatedIonChannel,7(P2RX7)(MiddleRegion)Peptide

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  • 產品廠商：半導體
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簡單介紹：
PurinergicReceptorP2X,Ligand-GatedIonChannel,7(P2RX7)(MiddleRegion)Peptide
詳情介紹：
Blocked Antibody anti-P2RX7 antibody (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7) (Middle Region) (ABIN2776151)
Characteristics This is a synthetic peptide designed for use in combination with anti-P2RX7 antibody (Catalog #: ARP35112_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: MGC20089, P2X7

Protein Interaction Partner: ACTB,EMP3,PANX1,SVIL

Protein Size: 595
Molecular Weight 68 kDa
Gene ID 5027
NCBI Accession NM_002562, NP_002553
UniProt Q99572
Research Area Neurology
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.