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  • 產(chǎn)品名稱：MatrixMetallopeptidase16(Membrane-inserted)(MMP16)(N-Term)Peptide

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MatrixMetallopeptidase16(Membrane-inserted)(MMP16)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-MMP16 antibody (Matrix Metallopeptidase 16 (Membrane-inserted)) (N-Term) (ABIN2782697)
Characteristics This is a synthetic peptide designed for use in combination with anti-MMP16 antibody (Catalog #: ARP46674_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another soluble form of the protein. Both forms of the protein activate MMP2 by cleavage.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Alias Symbols: MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP, C8orf57

Protein Interaction Partner: ERBB2,KISS1,LRP1

Protein Size: 607
Molecular Weight 56 kDa
Gene ID 4325
NCBI Accession NM_005941, NP_005932
UniProt P51512
Research Area Angiogenesis, Proteolysis / Ubiquitin, Extracellular Matrix, Matrix Metalloproteinases, Metalloprotease
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.