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  • 產(chǎn)品名稱：LysylOxidase-Like1(LOXL1)(MiddleRegion)Peptide

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  • 產(chǎn)品廠商：半導(dǎo)體
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簡單介紹：
LysylOxidase-Like1(LOXL1)(MiddleRegion)Peptide
詳情介紹：
Blocked Antibody anti-LOXL1 antibody (Lysyl Oxidase-Like 1) (Middle Region) (ABIN2785879)
Characteristics This is a synthetic peptide designed for use in combination with anti-LOXL1 antibody (Catalog #: ARP54781_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: LOL, LOXL

Protein Interaction Partner: ELN,FBLN5,FBLN5

Protein Size: 574
Molecular Weight 53 kDa
Gene ID 4016
NCBI Accession NM_005576, NP_005567
UniProt Q08397
Research Area Metabolism, Amino Acids
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.