產(chǎn)品詳情

  • 產(chǎn)品名稱：ATPase,H+Transporting,Lysosomal56/58kDa,V1SubunitB2(ATP6V1B2)(N-Term)Peptide

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ATPase,H+Transporting,Lysosomal56/58kDa,V1SubunitB2(ATP6V1B2)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-ATP6V1B2 antibody (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2) (N-Term) (ABIN2786642)
Characteristics This is a synthetic peptide designed for use in combination with anti-ATP6V1B2 antibody (Catalog #: ARP56328_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2

Protein Size: 511
Molecular Weight 56 kDa
Gene ID 526
NCBI Accession NM_001693, NP_001684
UniProt P21281
Research Area Neurology, Metabolism
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.