Background
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Biotin-Ala-Ala-Phep(Oph)2 is a Peptidyl Aminoalkanephosphonate Inhibitor (DAP). The DAP inhibitors, which can be used as an alternative to the Chloromethyl Ketone derivatives (CMK), are serine specific and non- thio reactive. Features of Peptidyl Amino-alkanephosphonate (DAP): non-alkylating stable in aqueous solution minimal toxicity serine specific cell permeable.
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