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  • 產(chǎn)品名稱：AT13148

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  • 產(chǎn)品廠商：TargetMol
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簡單介紹：
AT13148
詳情介紹：
Purpose AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.
Characteristics Target: Akt inhibitor, ROCK inhibitor,S6 Kinase inhibitor, PKA inhibitor
Receptor: PKA,ROCK2,ROCK1,p70S6K,Akt1,Akt3,SGK3,RSK1,Akt2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 97?% +
Formula C17H16ClN3O
Solubility 200 mM in DMSO
Molecular Weight 313.78 g/mol
CAS-No 1056901-62-2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months