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Purpose
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A carnitine palmitoyltransferase I (CPT1) inhibitor
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Characteristics
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R-(+)-Etomoxir is a carnitine palmitoyltransferase I (CPT1) inhibitor which is required for the oxidation of long chain acyl CoA esters. It inhibits β-oxidation in mitochondria and shown to inhibit biosynthesis of cardiolipin from exogenous fatty acid in H9c2 cells. Potential antidiabetic drug.
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Purity
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≥ 98?% by HPLC
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Chemical Name
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(R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid, ethyl ester
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Formula
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C??H??ClO?
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Permeability
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Cell-permeable
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Solubility
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DMSO (>8 mg/ml)
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