|
Purpose
|
A potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK)
|
|
Characteristics
|
AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK) (IC?? = 0. 5 nM) with potential antineoplastic activity.
|
|
Purity
|
≥ 98?% by HPLC
|
|
Chemical Name
|
N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide; CC-292
|
|
Formula
|
C??H??FN?O?
|
|
Permeability
|
Cell-permeable
|
|
Solubility
|
DMSO (>50 mg/ml)
|
