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  • 產(chǎn)品名稱：(R,R)-Hymeglusin

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  • 產(chǎn)品廠商：Biovision
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簡(jiǎn)單介紹：
(R,R)-Hymeglusin
詳情介紹：
Purpose A specific and irreversable inhibitor of HMG-CoA
Characteristics (R,R)-Hymeglusin is a specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. It is a fungal beta-lactone that inhibits mevalonate biosynthesis and is a good target for statins. It displays antimicrobial and anti-fungal activity.
Purity ≥ 95?% by HPLC
Chemical Name (2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Formula C??H??O?
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 324.41 g/mol
CAS-No 29066-42-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months