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Purpose
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An adenylate cyclase inhibitor
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Characteristics
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2’, 5’- Dideoxyadenosine is a cell-permeable inhibitor of adenylate cyclase (IC?? = 2.7 μM). Inhibits growth and causes cell differentiation (1.5 μM) in K562 cells.
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Purity
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≥ 98?% by HPLC
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Chemical Name
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2',5'-Dideoxy-D-adenosine; 2',5'-DDA
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Formula
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C??H??N?O?
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Permeability
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Cell-permeable
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Solubility
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H?O (~20 mg/ml, warming) or DMSO (~ 30 mg/ml)
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