Purpose
|
A histone demethylase (HDM) inhibitor and an epigenetic modulator
|
Characteristics
|
AS8351 is a histone demethylase (HDM) inhibitor and an epigenetic modulator. In combination with eight other small molecules (called 9C), AS8351 enables conversion of human fibroblasts into cardiomyocyte-like cells.
|
Purity
|
≥ 98?% by TLC
|
Chemical Name
|
2-Hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone; NSC-51355
|
Formula
|
C??H??N?O?
|
Permeability
|
Cell-permeable
|
Solubility
|
DMSO
|