產(chǎn)品詳情
簡單介紹:
Mouseanti-HumanIg(LightChain),(Chainkappa)Antibody(PE)
詳情介紹:
Clone | A8B5 |
Isotype | IgG1 |
Purification | Size-exclusion chromatography. |
Alternative Name | Immunoglobulin |
Background | Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5?kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. |
Research Area | Secondary Antibodies, Virology |
Application Notes |
Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
Restrictions | For Research Use only |
Buffer | PBS containing 15 mM sodium azide as preservative and 0.2?% (w/v) high-grade BSA (Protease free) as stabilizer. |
Preservative | Sodium azide |
Precaution of Use | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Storage | 4 °C |
Storage Comment |
Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light. Shelf life: One year from despatch. |
Expiry Date | 12 months |
Supplier Images |
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Background publications |
Avilés-Salas, Chanona-Vilchis, Candelaria-Hernández, Pe?a-Torres, Cuéllar-Mendoza: "[Plasmoblastic lymphoma initially recognized as ovarian tumor]." in: Ginecología y obstetricia de México, Vol. 80, Issue 6, pp. 430-4, 2012 (PubMed).
Di Bartolo, Hyjek, Keller, Guasparri, Deng, Sun, Chadburn, Knowles, Cesarman: "Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposi's sarcoma-associated herpesvirus lytic reactivation in primary effusion lymphoma." in: Journal of virology, Vol. 83, Issue 9, pp. 4308-15, 2009 (PubMed). Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, 2008 (PubMed). Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, 1999 (PubMed). Siddiqui, Brandriss: "The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences." in: Molecular and cellular biology, Vol. 9, Issue 11, pp. 4706-12, 1990 (PubMed). Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed). |