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  • 產(chǎn)品名稱：NuclearCapBindingProteinSubunit1,80kDa(NCBP1)(N-Term)Peptide

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簡單介紹：
NuclearCapBindingProteinSubunit1,80kDa(NCBP1)(N-Term)Peptide
詳情介紹：
Blocked Antibody anti-Nuclear Cap Binding Protein Subunit 1, 80kDa (NCBP1) (N-Term) antibody (ABIN2778796)
Characteristics This is a synthetic peptide designed for use in combination with anti-NCBP1 antibody (Catalog #: ARP40396_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background NCBP1 is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: CBP80, MGC2087, NCBP, Sto1

Protein Interaction Partner: EIF4G1,EIF4G2,NCBP2,STAU1,BNIP1,BNIP3,EIF4G1,EIF4G2,HNRNPF,HNRNPH1,NCBP2,RNF40,RPS6KB1,SNRPA1,STAU1,BNIP1,BNIP2,BNIP3,EIF4G1,HNRNPF,HNRNPH1,NCBP2,RNF40,SRSF9

Protein Size: 790
Molecular Weight 92 kDa
Gene ID 4686
NCBI Accession NM_002486, NP_002477
UniProt Q09161
Research Area DNA/RNA, Chromatin and Nuclear Signaling
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.