產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：Clozapine

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  • 產(chǎn)品廠商：TargetMol
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簡(jiǎn)單介紹：
Clozapine
詳情介紹：
Purpose A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.
Characteristics Tradename: CLOZARIL
Source of Compound: synthetic, HF-1854
Target: Histamine Receptor antagonist,5-HT receptor antagonist,AChR antagonist,Adrenergic Receptor agonist ,Dopamine Receptor antagonist
Receptor: Histamine receptor,5-HT Receptor,Muscarinic AChR,β-adrenergic receptor,Dopamine receptor
Status: USP, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98?%
Formula C18H19ClN4
Solubility Water: 11.8 mg/L
Molecular Weight 326.82 g/mol
CAS-No 5786-21-0
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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image for Clozapine (ABIN4869869) Clozapine