產(chǎn)品詳情
簡單介紹:
AR-42(HDAC-42)
詳情介紹:
Purpose | A potent HDAC inhibitor |
Characteristics | AR-42 is a potent histone deacetylase inhibitor (HDACi). It induces growth inhibition, cell- cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 also promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21 and exhibits in vitro and ex vivo biologic activity against malignant mast cells. |
Purity | ≥ 98?% by HPLC |
Chemical Name | S)-N-hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide |
Formula | C??H??N?O? |
Permeability | Cell-permeable |
Solubility | DMSO (~ 20 mg/ml) or EtOH (~ 20 mg/ml |
Molecular Weight | 312.36 g/mol |
CAS-No | 935881-37-1 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and light |
Storage | -20 °C |
Expiry Date | 36 months |