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產(chǎn)品名稱:Mouseanti-ChickenIgAAntibody(Biotin)
產(chǎn)品型號:
產(chǎn)品廠商:Acris-antibodies
產(chǎn)品文檔:
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簡單介紹:
Mouseanti-ChickenIgAAntibody(Biotin)
詳情介紹:
Product details
Product details
Clone
A-1
Isotype
IgG2b
Target details
Target details
Background
Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15?% of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.Synonyms: Chicken Immunoglobulin A
Molecular Weight
160 kDa
Research Area
Immunology, Secondary Antibodies
Application Details
Application Details
Application Notes
ELISA. Flow Cytometry: < / = 1?μg/10^6 cells. Immunofluorescence.
Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
Handling
Concentration
0.5 mg/mL
Buffer
PBS containing 0.09?% Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -28 °C for longer.
References
References
Background publications
Chen, Lehmeyer, Cooper: "Evidence for an IgD homologue on chicken lymphocytes."
in:
Journal of immunology (Baltimore, Md. : 1950)
, Vol. 129, Issue 6, pp. 2580-5, 1983 (PubMed).